MacroGenics’ mission is to discover, develop and deliver to patients novel biologics for the treatment of cancer, autoimmune disorders and infectious diseases.  Learn More

  MacroGenics' Corporate Fact Sheet

Product Pipeline Highlights

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Program (Target) Indication Lead Opt. Pre-
Clin.
Ph
1
Ph
2
Ph
3
ONCOLOGY          
Margetuximab (Anti-HER2)(HER2) Gastroesophageal *  *  *  *  * 
Metastatic Breast *  *  *  *  * 
Solid Tumors *  *  *  *  * 
MGA271 (Anti-B7-H3)MGA271 (Anti-B7-H3)(B7-H3) Solid Tumors *  *  *  *  * 
MGD006 (CD123 x CD3)MGD006 (CD123 x CD3)(CD123 x CD3) AML *  *  *  *  * 
MGD007 (gpA33 x CD3)MGD007 (gpA33 x CD3)(gpA33 x CD3) Colorectal *  *  *  *  * 
OtherOther Solid Tumors *  *  *  *  * 
OtherOther Various *  *  *  *  * 
OtherOther(>75 Targ.) Solid & Liq. Tumors *  *  *  *  * 
AUTOIMMUNE          
Teplizumab (Anti-CD3)(CD3) T1D - Early Onset *  *  *  *  * 
T1D - At-Risk (NIH) *  *  *  *  * 
OtherOther(CD32B x CD79B) SLE, RA *  *  *  *  * 
OtherOther Autoimmune *  *  *  *  * 
INFECTIOUS DISEASES          
OtherOther Emerging Diseases *  *  *  *  * 
* In global collaboration with Eli Lilly & Co.

Overview

Since its founding in 2000, MacroGenics has applied its world-class antibody capabilities to create life-changing medicines. The company’s innovative product candidates leverage its fully-integrated capabilities and its multiple, proprietary technology platforms.

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Company Highlights

  • Robust pipeline in oncology, autoimmunity and infectious diseases
  • Partners include Boehringer Ingelheim, Gilead, Pfizer and Servier
  • Fully-integrated biologics capabilities across product development process 
  • Strong financial position and blue-chip investor base
  • Experienced management team and highly collaborative corporate culture 
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DART Platform

"10 Next-gen Biologics
Platforms to Watch”
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Partnering


Jan. '13 - Strategic alliance with Gilead on four DARTs.
Sep. '12 - Collaboration with Servier on multiple oncology DARTs.
Dec.  '11 - Collaboration with Servier on MGA271.
Oct. '10 - Global DART partnerships with Pfizer and Boehringer Ingelheim. Learn more