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MacroGenics’ Investigational Product Candidates

MacroGenics is a biopharmaceutical company focused on discovering and developing innovative monoclonal antibody-based therapeutics for the treatment of cancer, as well as autoimmune disorders and infectious diseases.

MacroGenics and its collaboration partners are conducting clinical studies that explore the use of product candidates developed by MacroGenics in different cancer settings. The product candidates listed below are investigational, in that they are being evaluated in clinical trials and are not yet approved for use by regulatory authorities. Approval by regulatory authorities around the world, such as the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA), is required to make our medicine available to the patients. Therefore, our priority is to enroll patients in clinical trials in order to obtain the data required for review and approval by regulatory authorities.

Hematological Malignancies

Acute Myeloid Leukemia (AML) and Myeloid Dysplastic Syndrome (MDS)

Relapsed/refractory B-cell Malignancies (including diffuse-large B cell lymphoma (DLBCL), follicular lymphoma (FL), mantle-cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), and acute lymphoblastic leukemia (ALL)

Solid Tumors

Bladder Cancer

Breast Cancer (Metastatic, HER2+)

Breast Cancer

Clear Cell Renal Cell Carcinoma

Colorectal Cancer

Gastric and Gastroesophageal Cancer



Non-small Cell Lung Cancer (NSCLC)

Ovarian Cancer

Pancreatic Cancer

Prostate Cancer

Renal Cell Carcinoma

Soft Tissue Sarcoma

Squamous Cell Carcinoma of the Head and Neck (SCCHN)

Thyroid Cancer

Cancer Resources

To learn about cancer and available treatments, please visit the following:

Please note – you will leave a website owned by MacroGenics, Inc.

MacroGenics is not responsible for any content on the third party website.

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